This exciting news was developed in New Delhi at the (NII) National Immunology Institute. The Supramolecular Insulin Assembly II (also known as “SIA-II”) has the ability to control glucose levels (in the intense research that has been conducted on lab animals) for three months with a single injection. Just for a comparison, the longest acting insulin injection available on the current market is effective for only to eighteen hours.
Protein folding is the unique process that is the basis of this extra-long lasting insulin injection. Human and bovine insulin is manipulated or “misfolded” to a form a new “supramolecule” which provides protection to the body as the drug is released very slowly over a long period of time. The drug is administered in a non-active form and becomes active only after being administered (this is known to increase the absorption, distribution and metabolization faster than drugs that are pre-active before entering the body).
Still in clinical trials and research that has only been performed on lab rats; this amazing new drug has been patented, commercialized and licensed to a Connecticut, United States based, pharmaceutical company called Life Science. Extended Delivery Pharmaceuticals (a subsidiary of Life Science) will be conducting the continuing, ongoing clinical trials of this new medication for diabetic patients.
In the lab studies conducted on rats, the researchers were thrilled to observe that compared to several regular insulin shots a day, one shot of this new medication every three months sustained the blood sugar levels in the animals. Human testing is scheduled to begin shortly and positive results are expected.
India, where over 50 million people that have diabetics live, pays an average of one-fourth of their total income to cover the cost of their diabetic medications they are currently using.
Although it is not a cure for the diabetes disease, the goal of Supramolecular Insulin Assembly II is to reduce the mental and financial burden of those who have to deal with diabetes by using super insulin.